Heptoprotective Role of Artemisia scoparia Waldst. and Kit Against CCl4-induced Toxicity in Rats

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Proficiencies of Artemisia scoparia against CCl4 induced DNA damages and renal toxicity in rat.

BACKGROUND Artemisia scoparia is traditionally used in the local system of medicine in kidney disorders. This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol extract against carbon tetrachloride (CCl4) provoked DNA damages and oxidative stress in kidneys of rat. METHODS Dried aerial parts of A. scoparia were powdered and extracted with methanol to obtain t...

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Phytotoxicity of major constituents of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit.

The phytotoxicity of the three major monoterpene constituents of the essential oil from leaves of Artemisia scoparia Waldst. & Kit. (redstem wormwood) was investigated. GC/GC-MS analysis revealed that the essential oil (yield 0.84%) is a complex mixture containing 19 monoterpenes, 7 sesquiterpenes and 15 other compounds--aliphatic alcohols, ketones, aromatic hydrocarbons and esters. The three m...

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Antioxidant and hepatoprotective effects of Artemisia dracunculus against CCl4-induced hepatotoxicity in rats

Objective: The present study was conducted to investigate the antioxidant and hepatoprotective activity of the hydro-alcoholic extract of aerial parts of Artemisia dracunculus (HAAD) against CCl4-induced hepatotoxicity in rats. Materials and Methods: The antioxidant activity was evaluated by reducing power, 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 20-azino-bis (3-ethylbenzothiazoline-6-sulf...

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مقایسه محتوای آرتمیزنین و اثر ضد مالاریایی درمنه خزری (Artemisia annua L.) و درمنه جارویی (Artemisia scoparia Waldst. & Kit.)

درمنه خزری (Artemisia annua L.) و درمنه جارویی (Artemisia scoparia Waldst. & Kit.) دو گیاه مهم دارویی هستند که در بسیاری از مناطق دنیا و ایران انتشار دارند. مالاریا یک بیماری واگیر در انسان و جانوران است که علت آن انگل تک‌یاخته‌ای آغازی پلاسمودیوم (Plasmodium) است. در این پژوهش ترکیب‌های ترپنوئیدی و آرتمیزنین از اندام‌های هوایی و ریشه این دو گونه درمنه استخراج شد. میزان ترپنوئیدها و آرتمیزنین ب...

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Antihypertensive Effects of Artemisia scoparia Waldst in Spontaneously Hypertensive Rats and Identification of Angiotensin I Converting Enzyme Inhibitors.

We investigated the antihypertensive effects of Artemisia scoparia (AS) in spontaneously hypertensive rats (SHR). The rats were fed diets containing 2% (w/w) hot water extracts of AS aerial parts for 6 weeks. The AS group had significantly lower systolic and diastolic blood pressure levels than the control group. The AS group also had lower angiotensin I converting enzyme (ACE) activity and ang...

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ژورنال

عنوان ژورنال: Polish Journal of Environmental Studies

سال: 2018

ISSN: 1230-1485,2083-5906

DOI: 10.15244/pjoes/74018